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Bruising after Zepbound (tirzepatide) injections is a common concern for patients starting this medication

Tirzepatide (the GIP-plus-GLP-1 dual agonist) has demonstrated superior weight loss compared to semaglutide monotherapy in SURMOUNT trials, with mean weight loss of up to 22.5% over 68 weeks

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Clinical evidence suggests no major contraindication between GLP-1 agonists and standard HRT regimens (estrogen-progesterone combinations or estrogen-only therapy)